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Safety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine
Author(s) -
Edson Duarte Moreira,
Nicholas Kitchin,
Xia Xu,
Samuel S. Dychter,
Stephen Lockhart,
Alejandra Gurtman,
John L. Perez,
Cristiano A. F. Zerbini,
Michael Dever,
Timothy W Jennings,
Donald Brandon,
Kevin D Can,
Michael Koren,
Douglas Denham,
Mezgebe Berhe,
David Fitz-Patrick,
Laura L Hammitt,
Nicola P. Klein,
Haylene Nell,
Georgina Keep,
Xingbin Wang,
Kenneth Koury,
Kena A. Swanson,
David Cooper,
Claire Lu,
Özlem Türeci,
Eleni Lagkadinou,
Dina B Tresnan,
Philip R. Dormitzer,
Uǧur Şahin,
William C. Gruber,
Kathrin U. Jansen
Publication year - 2022
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2200674
Subject(s) - reactogenicity , medicine , placebo , booster dose , randomized controlled trial , covid-19 , clinical trial , pediatrics , immunization , immunology , infectious disease (medical specialty) , disease , alternative medicine , pathology , antigen
Active immunization with the BNT162b2 vaccine (Pfizer-BioNTech) has been a critical mitigation tool against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the coronavirus disease 2019 (Covid-19) pandemic. In light of reports of waning protection occurring 6 months after the primary two-dose vaccine series, data are needed on the safety and efficacy of offering a third (booster) dose in persons 16 years of age or older.

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