Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico
Author(s) -
Lisa M. Dunkle,
Karen L. Kotloff,
Cynthia L. Gay,
Germán Áñez,
Jeffrey Adelglass,
Alejandro Quintín Barrat Hernández,
Wayne L. Harper,
Daniel M. Duncanson,
Monica A. McArthur,
Diana F. Florescu,
R. Scott McClelland,
Veronica Garcia-Fragoso,
Robert Riesenberg,
David B. Musante,
David L. Fried,
Beth Safirstein,
Mark McKenzie,
Robert Jeanfreau,
Jeffrey K. Kingsley,
Jeffrey A. Henderson,
Dakotah C. Lane,
Guillermo M. RuizPalacios,
Lawrence Corey,
Kathleen M. Neuzil,
Robert W. Coombs,
Alexander L. Greninger,
Julia Hütter,
Julie A. Ake,
Katherine R. Smith,
Wayne Woo,
Iksung Cho,
Gregory M. Glenn,
Filip Dubovsky
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2116185
Subject(s) - covid-19 , clinical trial , coronavirus , medicine , environmental health , virology , family medicine , disease , infectious disease (medical specialty) , outbreak
NVX-CoV2373 is an adjuvanted, recombinant spike protein nanoparticle vaccine that was shown to have clinical efficacy for the prevention of coronavirus disease 2019 (Covid-19) in phase 2b-3 trials in the United Kingdom and South Africa, but its efficacy had not yet been tested in North America.
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