Open AccessFractional Flow Reserve–Guided PCI as Compared with Coronary Bypass Surgery
Author(s) -
William F. Fearon,
Frederik M. Zimmermann,
Bernard De Bruyne,
Zsolt Piróth,
Albert H.M. van Straten,
L Székely,
Giedrius Davidavičius,
Gintaras Kalinauskas,
Samer Mansour,
Rajesh Kharbanda,
Nikolaos Östlund-Papadogeorgos,
Adel Aminian,
Keith G. Oldroyd,
Nawwar AlAttar,
Nikola Jagić,
JanHenk E. Dambrink,
Petr Kala,
Oskar Angerås,
Philip MacCarthy,
Olaf Wendler,
Filip Casselman,
Nils Witt,
Kreton Mavromatis,
Steven E.S. Miner,
Jaydeep Sarma,
Thomas Engstrøm,
Evald Christiansen,
Pim A.L. Tonino,
Michael J. Reardon,
Di Lu,
Victoria Ding,
Yuhei Kobayashi,
Daniel B. Mark,
Kenneth W. Mahaffey,
Manisha Desai,
Y. Joseph Woo,
Alan C. Yeung,
Nico H.J. Pijls,
Fame Study Investigators
Publication year - 2022
Publication title -
new england journal of medicine/the new england journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2112299
Subject(s) - medicine , conventional pci , percutaneous coronary intervention , myocardial infarction , cardiology , hazard ratio , stroke (engine) , fractional flow reserve , revascularization , timi , coronary artery disease , clinical endpoint , confidence interval , surgery , randomized controlled trial , mechanical engineering , coronary angiography , engineering
Patients with three-vessel coronary artery disease have been found to have better outcomes with coronary-artery bypass grafting (CABG) than with percutaneous coronary intervention (PCI), but studies in which PCI is guided by measurement of fractional flow reserve (FFR) have been lacking.