Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting
Author(s) -
Noam Barda,
Noa Dagan,
Yatir BenShlomo,
Eldad Kepten,
Jacob Waxman,
Reut Ohana,
Miguel A. Hernán,
Marc Lipsitch,
Isaac S. Kohane,
Doron Netzer,
Ben Y. Reis,
Ran D. Balicer
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2110475
Subject(s) - medicine , vaccination , adverse effect , context (archaeology) , confidence interval , adverse event reporting system , population , absolute risk reduction , immunology , environmental health , paleontology , biology
Preapproval trials showed that messenger RNA (mRNA)-based vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had a good safety profile, yet these trials were subject to size and patient-mix limitations. An evaluation of the safety of the BNT162b2 mRNA vaccine with respect to a broad range of potential adverse events is needed.
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