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Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes
Author(s) -
Juan P. Frías,
Melanie J. Davies,
Julio Rosenstock,
Federico C. Pérez Manghi,
Laura Fernández Landó,
Brandon K. Bergman,
Bing Liu,
Xuewei Cui,
Katelyn Brown
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2107519
Subject(s) - semaglutide , agonist , glucagon like peptide 1 receptor , type 2 diabetes , medicine , receptor , endocrinology , diabetes mellitus , glucagon like peptide 1 , liraglutide
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist that is under development for the treatment of type 2 diabetes. The efficacy and safety of once-weekly tirzepatide as compared with semaglutide, a selective GLP-1 receptor agonist, are unknown.

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