Dupilumab in Children with Uncontrolled Moderate-to-Severe Asthma
Author(s) -
Leonard B. Bacharier,
Jorge Máspero,
Constance H. Katelaris,
Alessandro Fiocchi,
Rémi Gag,
I. de Mir,
Neal Jain,
Lawrence Sher,
Xuezhou Mao,
Dongfang Liu,
Yi Zhang,
Asif Khan,
Upender Kapoor,
Faisal A. Khokhar,
Paul J. Rowe,
Yamo Deniz,
Marcella Ruddy,
Elizabeth Laws,
Naimish Patel,
David M. Weinreich,
George D. Yancopoulos,
Nikhil Amin,
Leda Mannent,
David J. Lederer,
Megan Hardin
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2106567
Subject(s) - dupilumab , asthma , medicine , pediatrics , immunology
Children with moderate-to-severe asthma continue to have disease complications despite the receipt of standard-of-care therapy. The monoclonal antibody dupilumab has been approved for the treatment of adults and adolescents with asthma as well as with other type 2 inflammatory diseases.
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