Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis
Author(s) -
Mark Lebwohl,
Linda Stein Gold,
Bruce Strober,
Kim Papp,
April W. Armstrong,
Jerry Bagel,
Leon Kircik,
Benjamin D. Ehst,
Hwanhee Hong,
Jennifer Soung,
Jeff Fromowitz,
Scott Guenthner,
Stephen C. Piscitelli,
David S. Rubenstein,
Philip M. Brown,
Anna M. Tallman,
Robert Bissonnette
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2103629
Subject(s) - medicine , plaque psoriasis , psoriasis , dermatology , medline , political science , law
Tapinarof cream is a topical aryl hydrocarbon receptor-modulating agent under investigation for the treatment of psoriasis. Tapinarof modulates the expression of interleukin-17 and the skin-barrier proteins filaggrin and loricrin.
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