Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 | Zendy

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Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

Author(s) -

Ewan C. Goligher,

Charlotte Bradbury,

Bryan J. McVerry,

Patrick R. Lawler,

Jeffrey S. Berger,

Michelle N. Gong,

Marc Carrier,

Harmony R. Reynolds,

Anand Kumar,

Alexis F. Turgeon,

Lucy Z. Kornblith,

Susan R. Kahn,

John C. Marshall,

Keri S. Kim,

Brett L. Houston,

Lennie Derde,

Mary Cushman,

Tobias Tritschler,

Derek Angus,

Lucas C. Godoy,

Zoe McQuilten,

BridgetAnne Kirwan,

Michael E. Farkouh,

Maria M. Brooks,

Roger Lewis,

Lindsay R. Berry,

Elizabeth Lorenzi,

Anthony Gordon,

Tania Ahuja,

Farah Al-Beidh,

Djillali Annane,

Yaseen M. Arabi,

Diptesh Aryal,

Lisa Baumann Kreuziger,

Abi Beane,

Zahra Bhimani,

Shailesh Bihari,

Henny H. Billett,

Lindsay Bond,

Marc J. M. Bonten,

Frank Brunkhorst,

Meredith Buxton,

Adrian Buzgau,

Lana A. Castellucci,

Sweta Chekuri,

JenTing Chen,

Allen C. Cheng,

Tamta Chkhikvadze,

Benjamin Coiffard,

Aira Contreras,

Todd W. Costantini,

Sophie de Brouwer,

Michelle A. Detry,

Abhijit Duggal,

Vladimír Džavík,

Mark B. Effron,

Heather Eng,

Jorge Escobedo,

Lise J Estcourt,

Brendan M. Everett,

Dean Fergusson,

Mark Fitzgerald,

Robert Fowler,

Joshua D. Froess,

Zhuxuan Fu,

J.P. Galanaud,

Benjamin Galen,

Sheetal Gandotra,

Timothy D. Girard,

Andrew L. Goodman,

Herman Goossens,

Cameron Green,

Yonatan Greenstein,

Peter L. Gross,

Rashan Haniffa,

Sheila M. Hegde,

Carolyn M. Hendrickson,

Alisa M. Higgins,

Alexander Hindenburg,

Aluko A. Hope,

James M Horowitz,

Christopher M. Horvat,

David T. Huang,

Kristin Hudock,

Beverley J. Hunt,

Mansoor Husain,

Robert C. Hyzy,

Jeffrey R. Jacobson,

Devachandran Jayakumar,

Norma Keller,

Akram Khan,

Yuri Kim,

Andrei Kindzelski,

Andrew J. King,

M. Margaret Knudson,

Aaron E. Kornblith,

Matthew Kutcher,

Michael Laffan,

François Lamontagne,

Grégoire Le Gal,

Christine M. Leeper,

Eric Leifer,

George Lim,

Felipe Gallego Lima,

Kelsey Linstrum,

Edward Litton,

José LópezSendón,

Sylvain Lother,

Nicole Marten,

Andréa Saud Marinez,

Mary Martinez,

Eduardo Mateos Garcia,

Stavroula Mavromichalis,

Daniel F. McAuley,

Emily G. McDonald,

Anna McGlothlin,

Shay McGuinness,

Saskia Middeldorp,

Stephanie K. Montgomery,

Paul Mouncey,

Srinivas Murthy,

Girish B. Nair,

Rahul Nair,

Alistair Nichol,

José Carlos Nicolau,

Brenda NunezGarcia,

John J. Park,

Pauline K. Park,

Rachael Parke,

Sam Parnia,

Jonathan Paul,

Mauricio Pompilio,

John G. Quigley,

Robert S Rosenson,

Natalia S Rost,

Kathy Rowan,

Fernanda O Santos,

Marlene Santos,

Mayler Olombrada Nunes de Santos,

Lewis Satterwhite,

Christina Saunders,

Jake Schreiber,

Roger Schutgens,

Christopher W. Seymour,

Deborah Siegal,

Delcio G Silva,

Aneesh B. Singhal,

Arthur S. Slutsky,

Dayna Solvason,

Simon Stanworth,

Anne Turner,

Wilma van Bentum-Puijk,

Frank L. van de Veerdonk,

Sean van Diepen,

Gloria VázquezGrande,

Lana Wahid,

Vanessa Wareham,

R. Jay Widmer,

Jennifer G. Wilson,

Eugene Yuriditsky,

Yongqi Zhong,

Scott Berry,

Colin J McArthur,

Matthew D. Neal,

Judith S. Hochman,

Steven A. Webb,

Ryan Zarychanski

Publication year - 2021

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa2103417

Subject(s) - interquartile range , medicine , odds ratio , confidence interval , randomized controlled trial , regimen , intensive care unit , intensive care medicine

Thrombosis and inflammation may contribute to morbidity and mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill patients with Covid-19.

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