Bimekizumab versus Adalimumab in Plaque Psoriasis
Author(s) -
Richard B. Warren,
Andrew Blauvelt,
Jerry Bagel,
Kim Papp,
Paul S. Yamauchi,
April W. Armstrong,
Richard Langley,
Veerle Vanvoorden,
Dirk De Cuyper,
Christopher L. Cioffi,
Luke Peterson,
Nancy Cross,
Kristian Reich
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2102388
Subject(s) - adalimumab , plaque psoriasis , psoriasis , medicine , monoclonal antibody , tumor necrosis factor alpha , monoclonal , tumor necrosis factor α , interleukin 17 , interleukin , dermatology , immunology , antibody , inflammation , cytokine
Bimekizumab is a monoclonal IgG1 antibody that selectively inhibits interleukin-17A and interleukin-17F. The efficacy and safety of bimekizumab as compared with the tumor necrosis factor inhibitor adalimumab in patients with moderate-to-severe plaque psoriasis have not been extensively examined.
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