Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19
Author(s) -
Jerald Sadoff,
Glenda Gray,
An Vandebosch,
Vicky Cárdenas,
Georgi Shukarev,
Beatriz Grinsztejn,
Paul Goepfert,
Carla Truyers,
Hein Fennema,
Bart Spiessens,
Kim Offergeld,
Gert C. Scheper,
Kimberly L. Taylor,
Merlin L. Robb,
John J. Treanor,
Dan H. Barouch,
Jeffrey J. Stoddard,
Martin Ryser,
Mary Marovich,
Kathleen M. Neuzil,
Lawrence Corey,
Nancy Cauwenberghs,
Tamzin Tanner,
Karin Hardt,
Javier RuizGuiñazú,
Mathieu Le Gars,
Hanneke Schuitemaker,
Johan Van Hoof,
Frank Struyf,
Macaya Douoguih
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2101544
Subject(s) - medicine , placebo , confidence interval , population , vaccine efficacy , randomized controlled trial , gastroenterology , immunology , vaccination , pathology , alternative medicine , environmental health
The Ad26.COV2.S vaccine is a recombinant, replication-incompetent human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a prefusion-stabilized conformation.
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