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AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis
Author(s) -
Johann Morelle,
Céline Maréchal,
Zanzhe Yu,
Huguette Debaix,
Tanguy Corre,
Mark Lambie,
Marion Verduijn,
Friedo W. Dekker,
P.H.L. Bovy,
Pieter Evenepoel,
Bert Bammens,
Rafael Selgas,
M. Auxiliadora Bajo,
Annemieke M. Coester,
Amadou Sow,
Nicolas Hautem,
Dirk G. Struijk,
Raymond T. Krediet,
JeanLuc Balligand,
Éric Goffin,
Ralph Crott,
Pierre Ripoche,
Simon Davies,
Olivier Devuyst
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2034279
Subject(s) - medicine , peritoneal dialysis , hemodialysis , hazard ratio , confidence interval , dialysis , ultrafiltration (renal) , relative risk , genotype , gastroenterology , urology , gene , genetics , biology , biochemistry
Variability in ultrafiltration influences prescriptions and outcomes in patients with kidney failure who are treated with peritoneal dialysis. Variants in AQP1 , the gene that encodes the archetypal water channel aquaporin-1, may contribute to that variability.

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