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Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates
Author(s) -
Edward E. Walsh,
Robert W. Frenck,
Ann R. Falsey,
Nicholas Kitchin,
Judith Absalon,
Alejandra Gurtman,
Stephen Lockhart,
Kathleen M. Neuzil,
Mark J. Mulligan,
Ruth Bailey,
Kena A. Swanson,
Ping Li,
Kenneth Koury,
Warren V. Kalina,
David Cooper,
Camila R. Fontes-Garfias,
PeiYong Shi,
Özlem Türeci,
Kristin Tompkins,
Kirsten E. Lyke,
Vanessa Raabe,
Philip R. Dormitzer,
Kathrin U. Jansen,
Uǧur Şahin,
William C. Gruber
Publication year - 2020
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2027906
Subject(s) - immunogenicity , covid-19 , virology , computational biology , medicine , biology , immunology , outbreak , antigen , infectious disease (medical specialty) , disease
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the resulting disease, coronavirus disease 2019 (Covid-19), have spread to millions of persons worldwide. Multiple vaccine candidates are under development, but no vaccine is currently available. Interim safety and immunogenicity data about the vaccine candidate BNT162b1 in younger adults have been reported previously from trials in Germany and the United States.

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