Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease | Zendy

Placide MbalaKingebeni | Zendy; Catherine Pratt | Zendy; Mbusa Mutafali-Ruffin | Zendy; Matthias Pauthner | Zendy; Faustin N. Bile | Zendy; Antoine Nkuba-Ndaye | Zendy; Allison Black | Zendy; Eddy Kinganda-Lusamaki | Zendy; Martin Faye | Zendy; Amuri Aziza | Zendy; Moussa Moïse Diagne | Zendy; Daniel MukadiBamuleka | Zendy; Bailey White | Zendy; James Hadfield | Zendy; Karthik Gangavarapu | Zendy; Nella Bisento | Zendy; Donatien Kazadi | Zendy; Bibiche Nsunda | Zendy; Marceline Akonga | Zendy; Olivier Tshiani | Zendy; John Misasi | Zendy; Aurélie Ploquin | Zendy; Victor Epaso | Zendy; Emilia Sana-Paka | Zendy; Yannick Tutu Tshia N’kasar | Zendy; Fabrice Mbika Mambu | Zendy; Francois Edidi | Zendy; Meris Matondo | Zendy; Junior Bula Bula | Zendy; Boubacar Diallo | Zendy; Mory Keïta | Zendy; Marie Roseline Darnycka Bélizaire | Zendy; Ibrahima Socé Fall | Zendy; Abdoulaye Yam | Zendy; Sabue Mulangu | Zendy; Anne W. Rimoin | Zendy; Elias Salfati | Zendy; Ali Torkamani | Zendy; Marc A. Suchard | Zendy; Ian Crozier | Zendy; Lisa E. Hensley | Zendy; Andrew Rambaut | Zendy; Ousmane Faye | Zendy; Amadou A. Sall | Zendy; Nancy J. Sullivan | Zendy; Trevor Bedford | Zendy; Kristian G. Andersen | Zendy; Michael R. Wiley | Zendy; Steve AhukaMundeke | Zendy; Jean-Jacques Muyembe Tamfum | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease

Author(s) -

Placide MbalaKingebeni,

Catherine Pratt,

Mbusa Mutafali-Ruffin,

Matthias Pauthner,

Faustin N. Bile,

Antoine Nkuba-Ndaye,

Allison Black,

Eddy Kinganda-Lusamaki,

Martin Faye,

Amuri Aziza,

Moussa Moïse Diagne,

Daniel MukadiBamuleka,

Bailey White,

James Hadfield,

Karthik Gangavarapu,

Nella Bisento,

Donatien Kazadi,

Bibiche Nsunda,

Marceline Akonga,

Olivier Tshiani,

John Misasi,

Aurélie Ploquin,

Victor Epaso,

Emilia Sana-Paka,

Yannick Tutu Tshia N’kasar,

Fabrice Mbika Mambu,

Francois Edidi,

Meris Matondo,

Junior Bula Bula,

Boubacar Diallo,

Mory Keïta,

Marie Roseline Darnycka Bélizaire,

Ibrahima Socé Fall,

Abdoulaye Yam,

Sabue Mulangu,

Anne W. Rimoin,

Elias Salfati,

Ali Torkamani,

Marc A. Suchard,

Ian Crozier,

Lisa E. Hensley,

Andrew Rambaut,

Ousmane Faye,

Amadou A. Sall,

Nancy J. Sullivan,

Trevor Bedford,

Kristian G. Andersen,

Michael R. Wiley,

Steve AhukaMundeke,

Jean-Jacques Muyembe Tamfum

Publication year - 2021

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa2024670

Subject(s) - ebola virus , virology , transmission (telecommunications) , virus , ebolavirus , disease , medicine , biology , computer science , telecommunications

During the 2018-2020 Ebola virus disease (EVD) outbreak in North Kivu province in the Democratic Republic of Congo, EVD was diagnosed in a patient who had received the recombinant vesicular stomatitis virus-based vaccine expressing a ZEBOV glycoprotein (rVSV-ZEBOV) (Merck). His treatment included an Ebola virus (EBOV)-specific monoclonal antibody (mAb114), and he recovered within 14 days. However, 6 months later, he presented again with severe EVD-like illness and EBOV viremia, and he died. We initiated epidemiologic and genomic investigations that showed that the patient had had a relapse of acute EVD that led to a transmission chain resulting in 91 cases across six health zones over 4 months. (Funded by the Bill and Melinda Gates Foundation and others.).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research