Intussusception after Rotavirus Vaccine Introduction in India | Zendy

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Intussusception after Rotavirus Vaccine Introduction in India

Author(s) -

Samarasimha Reddy N,

Nayana P. Nair,

Jacqueline E. Tate,

Varunkumar Thiyagarajan,

Sidhartha Giri,

Ira Praharaj,

Venkata Raghava Mohan,

Sudhir Babji,

M D Gupte,

Rashmi Arora,

Sunita Bidari,

Sowmiya Senthamizh,

Suhasini Mekala,

Krishna Babu Goru,

Bhaskar Reddy,

Padmalatha Pamu,

Rajendra P. Gorthi,

Manohar Badur,

Vittal Mohan,

Saroj Sathpathy,

Hiranya Kishor Mohanty,

Mrutunjay Dash,

Nirmal Kumar Mohakud,

Rajib Kumar Ray,

Prasantajyoti Mohanty,

Geeta Gathwala,

Suraj Chawla,

Madhu Gupta,

Rajkumar Gupta,

Suresh Goyal,

Pramod Sharma,

Mannancheril Abraham Mathew,

Tarun John K Jacob,

Sundaram Balasubramanian,

C. P. Girish Kumar,

Priyadarishini Dorairaj,

Muthukumaran Jagannatham,

Kulandaivel Murugiah,

Hemanthkumar Boopathy,

Raghul Maniam,

Rajamani Gurusamy,

S. Kumaravel,

Ashwitha Shenoy,

Hemant Jain,

Jayanta Kumar Goswami,

Ashish Wakhlu,

Vineeta Gupta,

Gopinath Vinayagamurthy,

Umesh D. Parashar,

Gagandeep Kang

Publication year - 2020

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa2002276

Subject(s) - rotavirus vaccine , intussusception (medical disorder) , rotavirus , medicine , immunization , virology , postmarketing surveillance , pediatrics , vaccination , environmental health , immunology , adverse effect , surgery , virus , antibody

A three-dose, oral rotavirus vaccine (Rotavac) was introduced in the universal immunization program in India in 2016. A prelicensure trial involving 6799 infants was not large enough to detect a small increased risk of intussusception. Postmarketing surveillance data would be useful in assessing whether the risk of intussusception would be similar to the risk seen with different rotavirus vaccines used in other countries.

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