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Atezolizumab for First-Line Treatment of PD-L1–Selected Patients with NSCLC
Author(s) -
Roy S. Herbst,
Giuseppe Giaccone,
Filippo de Marinis,
Niels Reinmuth,
A. Vergnenègre,
Carlos H. Barrios,
Masahiro Morise,
Enriqueta Felip,
Zoran Andrić,
Sarayut Lucien Geater,
Mustafa Özgüroğlu,
Wei Zou,
Alan Sandler,
Ida Enquist,
Kimberly M. Komatsubara,
Yu Deng,
Hiroshi Kuriki,
Xiaohui Wen,
Mark L. McCleland,
Simonetta Mocci,
Jacek Jassem,
David R. Spigel
Publication year - 2020
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1917346
Subject(s) - atezolizumab , medicine , oncology , lung cancer , hazard ratio , chemotherapy , population , immunohistochemistry , pembrolizumab , cancer , immunotherapy , confidence interval , environmental health
The efficacy and safety of the anti-programmed death ligand 1 (PD-L1) monoclonal antibody atezolizumab, as compared with those of platinum-based chemotherapy, as first-line treatment for patients with metastatic non-small-cell lung cancer (NSCLC) with PD-L1 expression are not known.

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