Open AccessEmapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis
Author(s) -
Franco Locatelli,
Michael B. Jordan,
Carl E. Allen,
Simone Cesaro,
Carmelo Rizzari,
Anupama Rao,
Barbara Degar,
Timothy P. Garrington,
Julián Sevilla,
M C Putti,
Franca Fagioli,
Martina Ahlmann,
José Luís Dapena,
M M Henry,
Fabrizio De Benedetti,
Alexei A. Grom,
G Lapeyre,
Philippe Jacqmin,
Maria Ballabio,
Cristina de Min
Publication year - 2020
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1911326
Subject(s) - hemophagocytic lymphohistiocytosis , primary (astronomy) , medicine , pediatrics , physics , disease , astronomy
Primary hemophagocytic lymphohistiocytosis is a rare syndrome characterized by immune dysregulation and hyperinflammation. It typically manifests in infancy and is associated with high mortality.
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