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A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants
Author(s) -
Sandra E. Juul,
Bryan A. Comstock,
Rajan Wadhawan,
Dennis E. Mayock,
Sherry E. Courtney,
Tonya Robinson,
Kaashif A. Ahmad,
Ellen BendelStenzel,
Mariana Baserga,
Edmund F. LaGamma,
L. Corbin Downey,
Raghavendra Rao,
Nancy Fahim,
Andrea Lampland,
Ivan D. Frantz,
Janine Y. Khan,
Michael Weiss,
Maureen Gilmore,
Robin K. Ohls,
Nishant Srinivasan,
Jorge Perez,
Victor McKay,
Phuong T. Vu,
Jean Lowe,
Karl Kuban,
T. Michael O’Shea,
Adam L. Hartman,
Patrick J. Heagerty
Publication year - 2020
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1907423
Subject(s) - neuroprotection , erythropoietin , randomized controlled trial , medicine , pediatrics
High-dose erythropoietin has been shown to have a neuroprotective effect in preclinical models of neonatal brain injury, and phase 2 trials have suggested possible efficacy; however, the benefits and safety of this therapy in extremely preterm infants have not been established.

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