Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer | Zendy

Kim N. | Zendy; Neeraj Agarwal | Zendy; Anders Bjartell | Zendy; Byung Ha Chung | Zendy; Andrea Juliana Pereira de Santana Gomes | Zendy; Robert Given | Zendy; Álvaro Juárez Soto | Zendy; Axel S. Merseburger | Zendy; Mustafa Özgüroğlu | Zendy; Hirotsugu Uemura | Zendy; Dingwei Ye | Zendy; Kris Deprince | Zendy; Vahid Naini | Zendy; Jinhui Li | Zendy; Shinta Cheng | Zendy; Margaret K. Yu | Zendy; Ke Zhang | Zendy; Julie S. Larsen | Zendy; Sharon McCarthy | Zendy; Simon Chowdhury | Zendy

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Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer

Author(s) -

Kim N.,

Neeraj Agarwal,

Anders Bjartell,

Byung Ha Chung,

Andrea Juliana Pereira de Santana Gomes,

Robert Given,

Álvaro Juárez Soto,

Axel S. Merseburger,

Mustafa Özgüroğlu,

Hirotsugu Uemura,

Dingwei Ye,

Kris Deprince,

Vahid Naini,

Jinhui Li,

Shinta Cheng,

Margaret K. Yu,

Ke Zhang,

Julie S. Larsen,

Sharon McCarthy,

Simon Chowdhury

Publication year - 2019

Publication title -

new england journal of medicine

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1903307

Subject(s) - prostate cancer , androgen deprivation therapy , medicine , placebo , enzalutamide , castration , oncology , androgen receptor , androgen , antiandrogen , urology , cancer , pathology , hormone , alternative medicine

Apalutamide is an inhibitor of the ligand-binding domain of the androgen receptor. Whether the addition of apalutamide to androgen-deprivation therapy (ADT) would prolong radiographic progression-free survival and overall survival as compared with placebo plus ADT among patients with metastatic, castration-sensitive prostate cancer has not been determined.

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