Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma
Author(s) -
Noopur Raje,
Jesús G. Berdeja,
Yi Lin,
David S. Siegel,
Sundar Jagannath,
Deepu Madduri,
Michaela Liedtke,
Jacalyn Rosenblatt,
Marcela V. Maus,
Ashley Turka,
Lyh-Ping Lam,
Richard A. Morgan,
Kevin M. Friedman,
Monica Massaro,
Julie Wang,
Greg Russotti,
Zhihong Yang,
Timothy Campbell,
Kristen Hege,
Fabio Petrocca,
M. Travis Quigley,
Nikhil C. Munshi,
James N. Kochenderfer
Publication year - 2019
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1817226
Subject(s) - chimeric antigen receptor , car t cell therapy , multiple myeloma , cancer research , medicine , antigen , cell therapy , refractory (planetary science) , oncology , immunology , cell , t cell , biology , immune system , genetics , astrobiology
Preclinical studies suggest that bb2121, a chimeric antigen receptor (CAR) T-cell therapy that targets B-cell maturation antigen (BCMA), has potential for the treatment of multiple myeloma.
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