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Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
Author(s) -
Peter Schmid,
Sylvia Adams,
Hope S. Rugo,
Andreas Schneeweiss,
Carlos H. Barrios,
Hiroji Iwata,
Véronique Dièras,
Roberto Hegg,
SeockAh Im,
Gail S. Wright,
Volkmar Henschel,
Luciana Molinero,
Jane Yuet Ching Hui,
Roel Funke,
Amreen Husain,
Eric P. Winer,
Sherene Loi,
Leisha A. Emens
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1809615
Subject(s) - atezolizumab , triple negative breast cancer , paclitaxel , breast cancer , oncology , medicine , nab paclitaxel , hormone receptor , cancer , cancer research , immunotherapy , pembrolizumab
Unresectable locally advanced or metastatic triple-negative (hormone-receptor-negative and human epidermal growth factor receptor 2 [HER2]-negative) breast cancer is an aggressive disease with poor outcomes. Nanoparticle albumin-bound (nab)-paclitaxel may enhance the anticancer activity of atezolizumab.

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