An Outbreak of Synthetic Cannabinoid–Associated Coagulopathy in Illinois | Zendy

Amar H. Kelkar | Zendy; Nichole A. Smith | Zendy; Annia Martial | Zendy; Harsha Moole | Zendy; Michael D. Tarantino | Zendy; Jonathan Roberts | Zendy

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An Outbreak of Synthetic Cannabinoid–Associated Coagulopathy in Illinois

Author(s) -

Amar H. Kelkar,

Nichole A. Smith,

Annia Martial,

Harsha Moole,

Michael D. Tarantino,

Jonathan Roberts

Publication year - 2018

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1807652

Subject(s) - coagulopathy , medicine , brodifacoum , bleeding diathesis , outbreak , intensive care medicine , cannabinoid , anticoagulant , psychiatry , virology , platelet , receptor

In March and April 2018, more than 150 patients presented to hospitals in Illinois with coagulopathy and bleeding diathesis. Area physicians and public health organizations identified an association between coagulopathy and synthetic cannabinoid use. Preliminary tests of patient serum samples and drug samples revealed that brodifacoum, an anticoagulant, was the likely adulterant.

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