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Tranexamic Acid for the Prevention of Blood Loss after Vaginal Delivery
Author(s) -
Loı̈c Sentilhes,
Norbert Winer,
Élie Azria,
Marie-Victoire Sénat,
Camille Le Ray,
Delphine Vardon,
F. Perrotin,
Raoul Desbrière,
Florent Fuchs,
Gilles Kayem,
Guillaume Ducarme,
Muriel Doret-Dion,
C. Huissoud,
Caroline Bohec,
Philippe Deruelle,
Astrid Darsonval,
Jean-Marie Chrétien,
Aurélien Seco,
Valérie Daniel,
Catherine DeneuxTharaux
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1800942
Subject(s) - tranexamic acid , medicine , uterotonic , placebo , relative risk , randomization , oxytocin , randomized controlled trial , confidence interval , anesthesia , vaginal delivery , postpartum period , obstetrics , pregnancy , gynecology , surgery , blood loss , alternative medicine , pathology , biology , genetics
The use of tranexamic acid reduces mortality due to postpartum hemorrhage. We investigated whether the prophylactic administration of tranexamic acid in addition to prophylactic oxytocin in women with vaginal delivery would decrease the incidence of postpartum hemorrhage.

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