Type 2 Poliovirus Detection after Global Withdrawal of Trivalent Oral Vaccine
Author(s) -
Isobel M. Blake,
Margarita Pons-Salort,
Natalie A. Molodecky,
Ousmane M. Diop,
Paul Chenoweth,
Ananda S Bandyopadhyay,
Michel Zaffran,
Roland W. Sutter,
Nicholas C. Grassly
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1716677
Subject(s) - poliovirus , virology , serotype , outbreak , inactivated poliovirus vaccine , medicine , poliomyelitis eradication , virus
Mass campaigns with oral poliovirus vaccine (OPV) have brought the world close to the eradication of wild poliovirus. However, to complete eradication, OPV must itself be withdrawn to prevent outbreaks of vaccine-derived poliovirus (VDPV). Synchronized global withdrawal of OPV began with serotype 2 OPV (OPV2) in April 2016, which presented the first test of the feasibility of eradicating all polioviruses.
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