Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation
Author(s) -
Mark E. Robson,
SeockAh Im,
Elżbieta Senkus,
Binghe Xu,
Susan M. Domchek,
Norikazu Masuda,
Suzette Delaloge,
Wěi Li,
Nadine Tung,
Anne Armstrong,
Wenting Wu,
Carsten Goessl,
Sarah Runswick,
Pierfranco Conté
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1706450
Subject(s) - olaparib , medicine , oncology , parp inhibitor , hazard ratio , brca mutation , metastatic breast cancer , breast cancer , eribulin , cancer , confidence interval , gene , polymerase , poly adp ribose polymerase , biochemistry , chemistry
Olaparib is an oral poly(adenosine diphosphate-ribose) polymerase inhibitor that has promising antitumor activity in patients with metastatic breast cancer and a germline BRCA mutation.
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