The Role of PIEZO2 in Human Mechanosensation | Zendy

Alexander T. Chesler | Zendy; Marcin Szczot | Zendy; Diana BharuchaGoebel | Zendy; Marta Čeko | Zendy; Sandra Donkervoort | Zendy; Claire M. Laubacher | Zendy; Leslie H. Hayes | Zendy; Katharine E. Alter | Zendy; Cristiane Zampieri | Zendy; C. J. Stanley | Zendy; A. Micheil Innes | Zendy; Jean K. Mah | Zendy; Carla Grosmann | Zendy; Nathaniel Bradley | Zendy; David Nguyen | Zendy; A. Reghan Foley | Zendy; Claire E. Le Pichon | Zendy; Carsten G. Bönnemann | Zendy

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The Role of PIEZO2 in Human Mechanosensation

Author(s) -

Alexander T. Chesler,

Marcin Szczot,

Diana BharuchaGoebel,

Marta Čeko,

Sandra Donkervoort,

Claire M. Laubacher,

Leslie H. Hayes,

Katharine E. Alter,

Cristiane Zampieri,

C. J. Stanley,

A. Micheil Innes,

Jean K. Mah,

Carla Grosmann,

Nathaniel Bradley,

David Nguyen,

A. Reghan Foley,

Claire E. Le Pichon,

Carsten G. Bönnemann

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1602812

Subject(s) - mechanosensation , proprioception , neuroscience , medicine , physical medicine and rehabilitation , psychology , ion channel , receptor

The senses of touch and proprioception evoke a range of perceptions and rely on the ability to detect and transduce mechanical force. The molecular and neural mechanisms underlying these sensory functions remain poorly defined. The stretch-gated ion channel PIEZO2 has been shown to be essential for aspects of mechanosensation in model organisms.

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