Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria | Zendy

Nicholas J. White | Zendy; Tran Thanh Duong | Zendy; Chirapong Uthaisin | Zendy; François Nosten | Zendy; Aung Pyae Phyo | Zendy; Borimas Hanboonkunupakarn | Zendy; Sasithon Pukrittayakamee | Zendy; Podjanee Jittamala | Zendy; Kittiphum Chuthasmit | Zendy; Ming S. Cheung | Zendy; Yiyan Feng | Zendy; Ruobing Li | Zendy; Baldur Magnusson | Zendy; Marc Sultan | Zendy; Daniela Wieser | Zendy; Xiaolei Xun | Zendy; Rong Zhao | Zendy; Thierry T. Diagana | Zendy; Peter Pertel | Zendy; F. Joel Leong | Zendy

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Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

Author(s) -

Nicholas J. White,

Tran Thanh Duong,

Chirapong Uthaisin,

François Nosten,

Aung Pyae Phyo,

Borimas Hanboonkunupakarn,

Sasithon Pukrittayakamee,

Podjanee Jittamala,

Kittiphum Chuthasmit,

Ming S. Cheung,

Yiyan Feng,

Ruobing Li,

Baldur Magnusson,

Marc Sultan,

Daniela Wieser,

Xiaolei Xun,

Rong Zhao,

Thierry T. Diagana,

Peter Pertel,

F. Joel Leong

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1602250

Subject(s) - malaria , plasmodium falciparum , primaquine , biology , gametocyte , malarial parasites , plasmodium vivax , vivax malaria , virology , immunology , chloroquine

KAF156 belongs to a new class of antimalarial agents (imidazolopiperazines), with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites.

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