Efficacy of a Single-Dose, Inactivated Oral Cholera Vaccine in Bangladesh | Zendy

Firdausi Qadri | Zendy; Thomas F. Wierzba | Zendy; Mohammad Ali | Zendy; Fahima Chowdhury | Zendy; Ashraful Islam Khan | Zendy; Amit Saha | Zendy; Iqbal Ansary Khan | Zendy; Muhammad Asaduzzaman | Zendy; Afroza Akter | Zendy; Arifuzzaman Khan | Zendy; Yasmin Ara Begum | Zendy; Taufiqur Rahman Bhuiyan | Zendy; Farhana Khanam | Zendy; Mohiul Islam Chowdhury | Zendy; Taufiqul Islam | Zendy; Atique Iqbal Chowdhury | Zendy; Anisur Rahman | Zendy; Shah Alam Siddique | Zendy; Young A. You | Zendy; Deok R. Kim | Zendy; Ashraf Siddik | Zendy; Nirod Chandra Saha | Zendy; Alamgir Kabir | Zendy; Alejandro Cravioto | Zendy; Sachin N. Desai | Zendy; Ajit Singh | Zendy; John D. Clemens | Zendy

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Efficacy of a Single-Dose, Inactivated Oral Cholera Vaccine in Bangladesh

Author(s) -

Firdausi Qadri,

Thomas F. Wierzba,

Mohammad Ali,

Fahima Chowdhury,

Ashraful Islam Khan,

Amit Saha,

Iqbal Ansary Khan,

Muhammad Asaduzzaman,

Afroza Akter,

Arifuzzaman Khan,

Yasmin Ara Begum,

Taufiqur Rahman Bhuiyan,

Farhana Khanam,

Mohiul Islam Chowdhury,

Taufiqul Islam,

Atique Iqbal Chowdhury,

Anisur Rahman,

Shah Alam Siddique,

Young A. You,

Deok R. Kim,

Ashraf Siddik,

Nirod Chandra Saha,

Alamgir Kabir,

Alejandro Cravioto,

Sachin N. Desai,

Ajit Singh,

John D. Clemens

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1510330

Subject(s) - cholera , medicine , cholera vaccine , placebo , regimen , virology , vibrio cholerae , biology , bacteria , genetics , alternative medicine , pathology

A single-dose regimen of the current killed oral cholera vaccines that have been prequalified by the World Health Organization would make them more attractive for use against endemic and epidemic cholera. We conducted an efficacy trial of a single dose of the killed oral cholera vaccine Shanchol, which is currently given in a two-dose schedule, in an urban area in which cholera is highly endemic.

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