Corticosteroid Suppression of VEGF-A in Infantile Hemangioma-Derived Stem Cells | Zendy

Shoshana Greenberger | Zendy; Elisa Boscolo | Zendy; Irit Adini | Zendy; John B. Mulliken | Zendy; Joyce Bischoff | Zendy

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Corticosteroid Suppression of VEGF-A in Infantile Hemangioma-Derived Stem Cells

Author(s) -

Shoshana Greenberger,

Elisa Boscolo,

Irit Adini,

John B. Mulliken,

Joyce Bischoff

Publication year - 2010

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa0903036

Subject(s) - vasculogenesis , medicine , stem cell , angiogenesis , hemangioma , vascular endothelial growth factor , in vivo , cancer research , pathology , biology , microbiology and biotechnology , progenitor cell , vegf receptors

Corticosteroids are commonly used to treat infantile hemangioma, but the mechanism of action of this therapy is unknown. We investigated the effect of corticosteroids in a previously described in vivo model of infantile hemangioma and in cultured hemangioma-derived cells.

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