Open AccessAspirin and the Risk of Colorectal Cancer in Relation to the Expression of COX-2
Author(s) -
Andrew T. Chan,
Shuji Ogino,
Charles S. Fuchs
Publication year - 2007
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa067208
Subject(s) - aspirin , medicine , colorectal cancer , proportional hazards model , relative risk , confidence interval , cancer , oncology , cyclooxygenase , incidence (geometry) , carcinogenesis , gastroenterology , biology , enzyme , biochemistry , physics , optics
Regular use of aspirin reduces the risk of a colorectal neoplasm, but the mechanism by which aspirin affects carcinogenesis in the colon is not well understood.
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