Long-Term Follow-up of the West of Scotland Coronary Prevention Study | Zendy

Ian Ford | Zendy; Heather Murray | Zendy; Chris J. Packard | Zendy; James Shepherd | Zendy; Peter W. Macfarlane | Zendy; Stuart M. Cobbe | Zendy

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Long-Term Follow-up of the West of Scotland Coronary Prevention Study

Author(s) -

Ian Ford,

Heather Murray,

Chris J. Packard,

James Shepherd,

Peter W. Macfarlane,

Stuart M. Cobbe

Publication year - 2007

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa065994

Subject(s) - medicine , pravastatin , myocardial infarction , placebo , cardiology , statin , stroke (engine) , randomized controlled trial , mortality rate , surgery , cholesterol , mechanical engineering , alternative medicine , pathology , engineering

The West of Scotland Coronary Prevention Study was a randomized clinical trial comparing pravastatin with placebo in men with hypercholesterolemia who did not have a history of myocardial infarction, with an average follow-up of approximately 5 years. The combined outcome of death from definite coronary heart disease or definite nonfatal myocardial infarction was reduced from 7.9 to 5.5% (P<0.001) in the treatment group. Extended follow-up data were obtained for approximately 10 years after completion of the trial.

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