Randomized, Placebo-Controlled Trial of Inactivated Poliovirus Vaccine in Cuba | Zendy

Miguel Galindo | Zendy; P Kouri | Zendy; Roland W. Sutter | Zendy

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Randomized, Placebo-Controlled Trial of Inactivated Poliovirus Vaccine in Cuba

Author(s) -

Miguel Galindo,

P Kouri,

Roland W. Sutter

Publication year - 2007

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa054960

Subject(s) - medicine , poliovirus , seroconversion , inactivated poliovirus vaccine , poliomyelitis , vaccination , diphtheria , pediatrics , population , randomized controlled trial , virology , hib vaccine , immunogenicity , immunology , virus , antibody , environmental health , conjugate vaccine

After poliomyelitis has been eradicated, access to live polioviruses will be highly restricted and the use of oral poliovirus vaccine (OPV) will probably be discontinued. Countries using OPV must decide whether to switch to inactivated poliovirus vaccine (IPV) or stop polio vaccination. Because data on the immunogenicity of IPV in tropical developing countries are limited, we conducted a randomized, controlled trial of IPV in Cuba.

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