Genetic Modifiers of Lung Disease in Cystic Fibrosis
Author(s) -
Mitchell L. Drumm,
Michael W. Konstan,
Mark Schluchter,
Allison Handler,
Rhonda G. Pace,
Fei Zou,
Maimoona A. Zariwala,
David C. Fargo,
Airong Xu,
John M. Dunn,
Rebecca Darrah,
Ruslan Dorfman,
Andrew J. Sandford,
Mary Corey,
Julian Zielenski,
Peter R. Durie,
Katrina A.B. Goddard,
James R. Yankaskas,
Fred A. Wright,
Michael R. Knowles
Publication year - 2005
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa051469
Subject(s) - cystic fibrosis , medicine , genotype , cystic fibrosis transmembrane conductance regulator , odds ratio , gastroenterology , allele , disease , respiratory disease , lung , pathology , immunology , genetics , gene , biology
Polymorphisms in genes other than the cystic fibrosis transmembrane conductance regulator (CFTR) gene may modify the severity of pulmonary disease in patients with cystic fibrosis.
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