A Longitudinal Study of Abnormalities on MRI and Disability from Multiple Sclerosis | Zendy

Peter Brex | Zendy; Olga Ciccarelli | Zendy; J O’Riordan | Zendy; Michael Sailer | Zendy; Alan J. Thompson | Zendy; David H. Miller | Zendy

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A Longitudinal Study of Abnormalities on MRI and Disability from Multiple Sclerosis

Author(s) -

Peter Brex,

Olga Ciccarelli,

J O’Riordan,

Michael Sailer,

Alan J. Thompson,

David H. Miller

Publication year - 2002

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa011341

Subject(s) - multiple sclerosis , medicine , expanded disability status scale , magnetic resonance imaging , optic neuritis , mcdonald criteria , lesion , spinal cord , central nervous system disease , brain size , radiology , pathology , psychiatry

In patients with isolated syndromes that are clinically suggestive of multiple sclerosis, such as optic neuritis or brain-stem or spinal cord syndromes, the presence of lesions as determined by T2-weighted magnetic resonance imaging (MRI) of the brain increases the likelihood that multiple sclerosis will develop. We sought to determine the relation between early lesion volume, changes in volume, and long-term disability.

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