Open AccessHow Does Progesterone Relax the Uterus in Pregnancy?
Author(s) -
Tamás Zakár,
Sam Mesiano
Publication year - 2011
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmcibr1100071
Subject(s) - medicine , uterus , pregnancy , obstetrics , gynecology , endocrinology , biology , genetics
Most of us owe our existence to the calming influence of progesterone on our mother's uterine muscle (the myometrium). By the third trimester of pregnancy, the myometrium is akin to a sleeping giant. Once awakened, it becomes one of the strongest muscles in the human body to facilitate birth. How progesterone calms the myometrium for most of pregnancy is a major unanswered question in obstetrics
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