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Identification of a Brazil-Nut Allergen in Transgenic Soybeans
Author(s) -
Julie A. Nordlee,
Steve L. Taylor,
Jeffrey Townsend,
Laurie A. Thomas,
Robert K. Bush
Publication year - 1996
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejm199603143341103
Subject(s) - radioallergosorbent test , brazil nut , allergen , nut , albumin , immunoglobulin e , food allergy , transgene , medicine , food science , allergy , biochemistry , biology , immunology , antibody , structural engineering , gene , engineering
The nutritional quality of soybeans (Glycine max) is compromised by a relative deficiency of methionine in the protein fraction of the seeds. To improve the nutritional quality, methionine-rich 2S albumin from the Brazil nut (Betholletia excelsa) has been introduced into transgenic soybeans. Since the Brazil nut is a known allergenic food, we assessed the allergenicity of the 2S albumin.

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