Methotrexate and Misoprostol to Terminate Early Pregnancy | Zendy

Richard Hausknecht | Zendy

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Methotrexate and Misoprostol to Terminate Early Pregnancy

Author(s) -

Richard Hausknecht

Publication year - 1995

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejm199508313330901

Subject(s) - medicine , misoprostol , methotrexate , pregnancy , obstetrics , gynecology , abortion , biology , genetics

Although medical termination of pregnancy is available in Europe and China as an alternative to surgical termination, political and social factors have blocked medical approaches to pregnancy termination in the United States. Methotrexate, which is toxic to trophoblastic tissue, has been used safely to treat unruptured ectopic pregnancies. This report describes the use of a single low dose of methotrexate followed by intravaginal misoprostol for the medical termination of early pregnancy.

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