Open AccessEfficient Synthesis of 2-Substituted Imidazoles by Palladium-Catalyzed Cross-Coupling with Benzylzinc Reagents
Author(s) -
Björn Åkermark,
Josefin Utas,
Berit Olofsson
Publication year - 2006
Publication title -
synlett
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.712
H-Index - 133
eISSN - 1437-2096
pISSN - 0936-5214
DOI - 10.1055/s-2006-948162
Subject(s) - chemistry , moiety , reagent , palladium , intramolecular force , imidazole , catalysis , coupling reaction , combinatorial chemistry , phenol , organic chemistry
Substituted benzylzinc reagents have been used in novel cross-coupling reactions with 2-iodo imidazoles to form compounds containing both a phenol and an imidazole moiety. The intramolecular hydrogen-bonding properties of these compounds were subsequently studied
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