Open AccessExploration of Sepsis-Associated Coagulopathy Severity and Pediatric Septic Shock Outcomes
Author(s) -
Jeremy Loberger,
Inmaculada Aban,
Priya Prabhakaran
Publication year - 2020
Publication title -
journal of pediatric intensive care
Language(s) - English
Resource type - Journals
eISSN - 2146-4618
pISSN - 2146-4626
DOI - 10.1055/s-0040-1713436
Subject(s) - medicine , septic shock , coagulopathy , pediatric intensive care unit , sepsis , retrospective cohort study , shock (circulatory) , intensive care unit , severe sepsis , intensive care medicine , cohort , mechanical ventilation , intensive care , emergency medicine , surgery
The objective of this study was to explore correlations between sepsis-associated coagulopathy (SAC) in pediatric septic shock and clinical outcomes. This was a retrospective cohort study of all children admitted to a single, academic pediatric intensive care unit with septic shock over 6 years. The prevalence of SAC was 93.5% with 61% being severe. Those with severe SAC were more likely to have a positive blood culture and have longer median duration of ventilation. All observed mortalities occurred in the severe SAC and indeterminate SAC groups. SAC is highly prevalent in pediatric septic shock and may predict important outcomes.