Open AccessSynthesis of Cyclohexane-Angularly-Fused Triquinanes
Author(s) -
Hongjun Jeon,
Jeffrey D. Winkler
Publication year - 2020
Publication title -
synthesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.885
H-Index - 140
eISSN - 1437-210X
pISSN - 0039-7881
DOI - 10.1055/s-0040-1705953
Subject(s) - cyclohexane , chemistry , quaternary carbon , organic chemistry , catalysis , enantioselective synthesis
Cyclohexane-angularly-fused triquinanes, 6-5-5-5 tetracycles, have attracted the attention of synthetic chemists due to their highly congested core structures and multiple quaternary carbon centers. This review focuses on the six completed total synthesis of naturally occurring cyclohexane-angularly-fused triquinanes in addition to seven notable methodologies that have been developed for the synthesis of these structures.