z-logo
open-access-imgOpen Access
A Simple Onlay Sellar Reconstruction Does Not Increase the Risk of Postoperative Cerebrospinal Fluid Leak in Well-Selected Patients
Author(s) -
Mark B. Chaskes,
Judd H. Fastenberg,
Swar Vimawala,
Gurston Nyquist,
Mindy Rabinowitz,
Chandala Chitguppi,
Meagan Falls,
Tomás Garzón-Muvdi,
Marc Rosen,
James J. Evans
Publication year - 2020
Publication title -
journal of neurological surgery. part b, skull base
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.488
H-Index - 42
eISSN - 2193-6331
pISSN - 2193-634X
DOI - 10.1055/s-0039-3402000
Subject(s) - medicine , pituitary adenoma , leak , neurosurgery , cerebrospinal fluid leak , surgery , cerebrospinal fluid , transsphenoidal surgery , cerebral spinal fluid , pituitary neoplasm , adenoma , pituitary gland , anesthesia , environmental engineering , hormone , engineering
Objective  A variety of endonasal sellar repair techniques have been described; many of which are complex, expensive, and carry potential morbidity but are felt to be necessary to prevent postoperative cerebrospinal fluid (CSF) leaks. We propose an effective, technically simple repair for select sellar defects utilizing an onlay of regenerated oxidized cellulose. Design  Retrospective review of patients from a single neurosurgeon who underwent endoscopic transsphenoidal surgery for pituitary adenoma and sellar reconstruction with only an onlay of regenerated oxidized cellulose. Patients were selected for this repair technique based on the absence of: (1) intraoperative identification of a CSF leak, (2) patulous diaphragm (expanded diaphragm sella herniating to or through sellar floor defect), and (3) other prohibiting comorbidities. Setting  The present study was conducted at a tertiary care center. Participants  In this study, pituitary adenoma patients were the participants. Outcome Measures  Main outcome measure of the study is postoperative CSF leak. Results  A total of 172 patients were identified. Of these, 153 were initial resections of pituitary adenomas. Gross total resection was achieved in 142 (82.6%) cases. Average tumor size was 2.2 ± 1.1 cm. Average tumor volume was 10.4 ± 19.8 cm 3 . No patients had intraoperative CSF leaks. All cases were repaired with only an onlay of regenerated oxidized cellulose. There were two postoperative CSF leaks (1.16%). Pre and postoperative SNOT-22 scores were 12.9 ± 11.9 and 14.3 ± 14.9 ( p  = 0.796), respectively. Conclusion  The use of an onlay of regenerated oxidized cellulose alone is an effective repair technique for select sellar defects. This technique does not result in increased postoperative CSF leak rates and avoids the higher relative cost and potential morbidity associated with more complex, multilayered closures.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here