Open AccessMetformin Intoxication with Severe Renal Damage: An Adolescent Case Report
Author(s) -
Ahmet Yöntem,
Nagehan Aslan,
Özden Özgür Horoz,
Aysun Karabay Beyazit,
Engin Melek,
Dinçer Yıldızdaş
Publication year - 2019
Publication title -
journal of pediatric intensive care
Language(s) - English
Resource type - Journals
eISSN - 2146-4618
pISSN - 2146-4626
DOI - 10.1055/s-0039-1695046
Subject(s) - metformin , medicine , biguanide , lactic acidosis , renal replacement therapy , intensive care medicine , acidosis , metabolic acidosis , acute kidney injury , insulin
Metformin is an oral antidiabetic medication which belongs to the class biguanide. Its most hazardous and life-threatening side effect is lactic acidosis which has been increasingly reported in recent years. Early diagnosis and aggressive treatment approaches have significantly reduced morbidity and mortality rates in metformin intoxication. In this case report, we emphasize the importance of early continuous renal replacement therapy in metformin-associated lactic acidosis in a 16-year-old patient who developed severe renal damage during the follow-up period of renal replacement therapy due to lactic acidosis after taking metformin in a suicide attempt.