Open AccessTransfusion-Associated Acute Lung Injury following Donor Granulocyte Transfusion in Two Pediatric Patients
Author(s) -
Didar Arslan,
Dinçer Yıldızdaş,
Özden Özgür Horoz,
Nagehan Aslan,
Göksel Leblebisatan
Publication year - 2019
Publication title -
journal of pediatric intensive care
Language(s) - English
Resource type - Journals
eISSN - 2146-4618
pISSN - 2146-4626
DOI - 10.1055/s-0039-1694991
Subject(s) - medicine , transfusion related acute lung injury , hypoxemia , granulocyte , anesthesia , lung , blood transfusion , blood product , transfusion therapy , intensive care medicine , surgery , pulmonary edema
Transfusion-associated acute lung injury (TRALI) is one of the complications seen due to transfusion. Hypoxemia and bilateral pulmonary infiltration in posteroanterior chest roentgenogram is seen in all cases during transfusion or within the first 6 hours; fever, hypotension, and pink frothy bleeding from endotracheal tube may also be seen. It can be seen following the administration of any blood product. The management strategies for TRALI include withholding the transfusion, positive pressure breathing support, and diuretics. There are few reported cases of TRALI occurring following donor granulocyte transfusion (DGT). In this article, we discuss two cases of TRALI following DGT transfusion.