Open AccessSuccessful Treatment of Recurrent Thrombosis Associated with Malignancy with Apixaban and Follow-up for 1 Year
Author(s) -
Timothy Boey,
Ashita Ashish Sule,
Ashish Anil Sule
Publication year - 2019
Publication title -
international journal of angiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.293
H-Index - 26
eISSN - 1615-5939
pISSN - 1061-1711
DOI - 10.1055/s-0039-1694780
Subject(s) - medicine , apixaban , malignancy , thrombosis , low molecular weight heparin , venous thromboembolism , surgery , heparin , warfarin , rivaroxaban , atrial fibrillation
This case report aims to highlight a successful example of using novel oral anticoagulants (NOACs), such as apixaban, to prevent recurrent venous thromboembolism (VTE) in patients with solid-organ malignancy, as an alternative to low-molecular weight heparin (LMWH). Discussed is the case of a 67-year-old woman diagnosed with recurrent thrombosis in the upper-right limb and malignancy of right breast with metastasis to the axillary lymph nodes. Over a follow-up period of more than 1 year, there was no recurrence of VTE and D-dimer decreased, illuminating the possibility of apixaban as an alternative form of treatment for recurrent VTE in patients with malignancy. This appears to be one of the first case reports in Singapore.