Open AccessNeonatal Functional and Structural Connectivity Are Associated with Cerebral Palsy at Two Years of Age
Author(s) -
Stephanie L. Merhar,
Elveda Gozdas,
Jean A. Tkach,
Nehal A. Parikh,
Beth M. KlineFath,
Lili He,
Weihong Yuan,
Mekibib Altaye,
James Leach,
Scott K. Holland
Publication year - 2019
Publication title -
american journal of perinatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.793
H-Index - 67
eISSN - 1098-8785
pISSN - 0735-1631
DOI - 10.1055/s-0039-1683874
Subject(s) - fractional anisotropy , medicine , diffusion mri , cerebral palsy , white matter , magnetic resonance imaging , corticospinal tract , functional magnetic resonance imaging , nuclear medicine , pediatrics , physical medicine and rehabilitation , radiology
The accuracy of structural magnetic resonance imaging (MRI) to predict later cerebral palsy (CP) in newborns with perinatal brain injury is variable. Diffusion tensor imaging (DTI) and task-based functional MRI (fMRI) show promise as predictive tools. We hypothesized that infants who later developed CP would have reduced structural and functional connectivity as compared with those without CP.