z-logo
open-access-imgOpen Access
Surgical Management Patterns of Sinonasal Malignancy: A Population-Based Study
Author(s) -
Qasim Husain,
Rohan Joshi,
Jennifer R. Cracchiolo,
Benjamin R. Roman,
Ian Ganly,
Viviane Tabar,
Marc A. Cohen
Publication year - 2018
Publication title -
journal of neurological surgery. part b, skull base
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.488
H-Index - 42
eISSN - 2193-6331
pISSN - 2193-634X
DOI - 10.1055/s-0038-1675233
Subject(s) - medicine , malignancy , cancer , cohort , retrospective cohort study , incidence (geometry) , surgical margin , surgery , general surgery , database , physics , computer science , optics
Objectives  Determining surgical trends and outcomes for sinonasal tumors is challenging given their low incidence and heterogeneous pathology. This study utilized the National Cancer Database (NCDB) to identify trends and outcomes associated with surgical management of sinonasal tumors. Design  Retrospective database analysis. Setting  National Cancer Database. Participants  Patients with sinonasal malignancies identified from the NCDB between 2010 and 2015. Main Outcome Measures  The primary outcome was the choice of surgical therapy used for sinonasal tumor resection: endoscopic versus open approach. Each was cohort analyzed with respect to various demographic and clinicopathologic factors. A treatment effect model was used to identify potential differences between surgical approaches. Survival was evaluated using Kaplan-Meier analysis. Results  A total of 10,193 patients with sinonasal malignancies were identified in the NCDB database; of these, 2,292 had a documented subsite, histology, and definitive surgical treatment with documented surgical approach and were included in the analysis. About 71.9% of patients had an open approach and 28.1% a purely endoscopic procedures. Tumor histology, treatment facility type, margin status, and length of stay were all variables that were associated with significant differences between the open and endoscopic cohort. Five-year survival rates for the open and endoscopic cohorts were not significantly different (59.6 and 60.8%, respectively). Conclusions  Assessment of the NCDB revealed that 28% patients with sinonasal malignancy were selected for endoscopic surgery. These patients had comparable oncologic outcomes to open resection.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here