Premium
Rapid improvement of autonomic and peripheral neuropathy after liver transplantation: A single case report
Author(s) -
McDougall Alan John,
Davies Leo,
McCaughan Geoffrey William
Publication year - 2002
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1053/jlts.2002.30588
Subject(s) - medicine , liver transplantation , cirrhosis , peripheral neuropathy , peripheral , autonomic nervous system , transplantation , pathogenesis , autonomic ganglion , gastroenterology , endocrinology , diabetes mellitus , heart rate , blood pressure
Peripheral and autonomic neuropathies are known but often unrecognized associations of cirrhosis from any cause. The pathogenesis of these effects are ill understood. Liver transplantation has been shown to reverse autonomic manifestations, but little evidence exists for an effect on peripheral neuropathy. This case report documents improvement in peripheral and autonomic neuropathy in a 40‐year‐old man with hepatitis B virus–related cirrhosis. A return to normal neurophysiological function was seen within 9 months of successful liver transplantation, suggesting a metabolic, rather than a structural, cause of such changes in the peripheral nervous system.