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Bone disease after liver transplantation
Author(s) -
Crippin Jeffrey S.
Publication year - 2001
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1053/jlts.2001.28516
Subject(s) - medicine , liver transplantation , metabolic bone disease , bone disease , transplantation , liver disease , calcitonin , bone mineral , osteoporosis , chronic liver disease , vitamin d and neurology , disease , bone density , surgery , gastroenterology , cirrhosis
Key Points 1 Bone disease is a common problem in patients with chronic liver disease and liver transplants. 2 The cause of bone disease in these patients is multifactorial. 3 Bone disease worsens initially after liver transplantation, with subsequent improvement over time. However, bone disease in liver transplant recipients is common with long‐term follow‐up. 4 Evaluation of these patients should include metabolic and hormonal evaluations in conjunction with dualenergy x‐ray absorptiometry or bone mineral density evaluation. 5 Treatment with calcium, vitamin D, and hormonal supplements should be considered when appropriate for patients awaiting and after liver transplantation. The use of bisphosphanates and calcitonin also should be considered, although published studies in these populations are few in number.