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Retransplantation for hepatitis C: Implications of different policies
Author(s) -
Rosen Hugo R.
Publication year - 2000
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1053/jlts.2000.18689
Subject(s) - medicine , liver transplantation , cirrhosis , hepatitis c virus , hepatitis c , gastroenterology , liver disease , surgery , transplantation , virus , immunology
Key Points 1. Approximately 20% of hepatitis C virus (HCV)‐positive liver transplant recipients develop evidence of allograft cirrhosis by year 5. 2. The prevalence of HCV infection in patients undergoing retransplantation has significantly increased since 1990. 3. Retransplantation for recurrent HCV is associated with poor long‐term survival. 4. Preoperative hyperbilirubinemia (billirubin ≥5 mg/dL) and renal failure predict poor outcome after retransplantation. 5. Retransplantation is the only viable option for patients in whom allografts fail because of recurrent HCV disease.