Chromophobe renal cell carcinoma or oncocytoma: a manner of challenge in frozen section diagnosis | Zendy

Farideh Baharzadeh | Zendy; Masoud Sadeghi | Zendy; Mazaher Ramezani | Zendy

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Chromophobe renal cell carcinoma or oncocytoma: a manner of challenge in frozen section diagnosis

Author(s) -

Farideh Baharzadeh,

Masoud Sadeghi,

Mazaher Ramezani

Publication year - 2019

Publication title -

biomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.498

H-Index - 26

eISSN - 2211-8039

pISSN - 2211-8020

DOI - 10.1051/bmdcn/2019090106

Subject(s) - oncocytoma , chromophobe cell , medicine , frozen section procedure , renal oncocytoma , pathology , renal mass , renal cell carcinoma , kidney , clear cell , nephrectomy

Chromophobe renal cell carcinoma (RCC) is a rare type of kidney neoplasm that is diagnosed in the 6th decade of life with similar incidence in male and female. We reported a case of 73-year-old man with a chief complaint of nocturia, frequency, dribbling and urinary retention with renal mass in ultrasound examination. Histologic examination and immunohistochemistry study revealed the diagnosis of chromophobe RCC which initially was mistaken for oncocytoma in frozen section diagnosis. The pathologist should be aware of this malignant entity and be cautious in diagnosing oncocytoma in frozen section and routine H & E staining.

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