Open AccessRapid and sensitive detection of neotame in instant grain beverages by paper‐based silver nanoparticles substrates
Author(s) -
Han Mingming,
Wei Weiwei,
Lu Hongmei,
Zhang Zhimin
Publication year - 2020
Publication title -
micro and nano letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.25
H-Index - 31
ISSN - 1750-0443
DOI - 10.1049/mnl.2020.0298
Subject(s) - repeatability , detection limit , silver nanoparticle , nanoparticle , instant , filter paper , substrate (aquarium) , raman scattering , materials science , relative standard deviation , chemistry , raman spectroscopy , analytical chemistry (journal) , chromatography , nanotechnology , food science , physics , optics , oceanography , geology
Neotame is an artificial sweetener with increasing consumption in recent years, excessive intake of it may bring potential health risk. In this work, a rapid method was developed to detect neotame in instant grain beverages, which was based on surface‐enhanced Raman scattering (SERS) technique and filter paper‐based silver nanoparticles (AgNPs@FP) substrates. The designed substrate exhibits good SERS activity with an enhancement factor of 10 5 because of the synergistic effect of the concentrated silver nanoparticles and filter paper. Meanwhile, the stability and repeatability of this fabricated substrate have been investigated with the relative standard deviation of 6.1%. In addition, it shows an excellent linear relationship ( R 2 = 0.997) between the SERS signal and the logarithm concentration of neotame with a wide concentration range (0.05–5 g/kg) in the quantitative analysis. The limit of detection of neotame can be as low as 0.01 g/kg in instant grain beverages, which is below the maximum allowable addition level for neotame in instant grain beverages set in China (GB2760‐2014, 0.16 g/kg). The proposed method has great potential for the identification and quantification of neotame in food safety applications with high sensitivity.